Dw/LD-related molecular polymorphism of DR4 β-chains
نویسندگان
چکیده
The results of this study demonstrate the existence of molecular heterogeneity (polymorphism) within DR beta-chains isolated from a single serologically defined DR phenotype, DR4. The data are consistent with the possibility that this polymorphism is related to the Dw/LD phenotype as defined with the cellular reagents, homozygous typing cells.
منابع مشابه
Brief Det~nitive Report Dw/ld-related Molecular Polymorphism of Dr4 Fl-chains*
Antigenic determinants encoded by genes of the HLA-D region have been related to at least three separate molecular complexes, DR, MB (also known as DC and LBE), and SB. At the cell surface each complex has a dimeric structure composed of a structurally conserved a-chain noncovalently associated with a polymorphic fl-chain. The DR and MB series of determinants have been extensively characterized...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 157 شماره
صفحات -
تاریخ انتشار 1983